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Effects of long- versus short-term exposure to the Mediterranean diet on the microvascular physiology and quality of life of healthy adults.

Effects of long- versus short-term exposure to the Mediterranean diet on the microvascular physiology and quality of life of healthy adults.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20190305002
Enrollment
Unknown
Registered
2019-03-05
Start date
2018-09-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CVD risk factors diet nutrition intervention

Interventions

Participants were given a food “starter” pack that included amongst others brown rice&#44
brown pasta&#44
lentils&#44
olive oil&#44
nuts&#44
chopped tomatoes and tomato puree. They were also given an information booklet&#44
guidelines on which foods constitute the Mediterranean diet (MD)&#44
and a recipe booklet to support the transition of their current diet to the MD prototype. Furthermore&#44
participants were encouraged to “swap” ingredients initially (i.e.&#44
swap white pasta and rice with whole&#45
grain varieties)&#44
instead of a radical dietary change from the beginning. ,Participants were left to follow their original (Mediterranean) diet.
Experimental Behavioral,No Intervention No treatment
Mediterranean diet non&#45
adherers,long&#45
term Mediterranean diet adherers

Sponsors

Sheffield Hallam University
Lead Sponsor
Aristotle University of Thessaloniki
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1) being an adult, 2) abstaining from any medication that could influence cardiovascular function, 3) being eager to participate, 4) being able to communicate efficiently in either the English or Greek language, depending on the study site, 5) adhering to the MD for the Thessaloniki participants, and 6) MD non-adherence for the Sheffield participants.

Exclusion criteria

Exclusion criteria: 1) participation in regular physical exercise (>60 min/week of structured or planned physical activity), 2) diagnosis of any chronic disease that could affect vascular function (such as diabetes, CVD, and hypertension), 3) pregnancy, and 4) smoking.

Design outcomes

Primary

MeasureTime frame
Endothelial dysfunction 4 weeks Laser Doppler flowmetry (LDF)

Secondary

MeasureTime frame
Quality of life 4 weeks WHO QoL,blood pressure 4 weeks blood pressure measurement,lipidemic profile 4 weeks finger prick test

Countries

UK

Contacts

Public ContactMarkos Klonizakis

Sheffield Hallam Uni

M.Klonizakis@shu.ac.uk+441142255697

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026