Prevalence of testosterone deficiency in male COPD patients in King Chulalongkorn Memorial Hospital Chronic obstructive pulmonary disease Testosterone deficiency
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. The 40-year or older male who was diagnosed of COPD by internist or pulmonologist. 2. The patients who give the informed consent and agree to follow to the study protocol.
Exclusion criteria
Exclusion criteria: 1. Underlying disease or history of these illnesses such as, 1.1 End stage renal disease which defined as creatinine clearance less than 15 ml/min/1.73 m2 1.2 Cirrhosis 1.3 History of active malignancy or recent chemotherapeutic medication within 5 years 1.4 Chronic anemia such as thalassemia who needed regular blood transfusion or finding of hemochromatosis 1.5 Active rheumatoid arthritis 1.6 Poor control of type 2 diabetes who have HbA1c > 8 % 1.7 Severe morbid obesity which defined as ≥ 30 kg/m2 1.8 Acute myocardial infarction or chest pain or dyspnea within 1 year 2. Diagnosed of hypogonadism before the inclusion period 3. Stop testosterone supplement and advice the patients to use as needed 4. Withdraw from the target 5. After acute exacerbation or admission who got systemic corticosteroid within 4 months 6. Available for listening, reading, or speaking in English 7. Contraindications of 6-minute walk test are 7.1 Acute myocardial infarction or chest pain (active) off prednisolone already 7.2 Systolic blood pressure > 180 mmHg or diastolic blood pressure > 120 mmHg and duration of pulse rate > 120 beat/min
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prevalence of testosterone deficiency in male COPD patients N/A Total testosterone level | — |
Secondary
| Measure | Time frame |
|---|---|
| N/A N/A N/A | — |
Countries
Thailand
Contacts
Endocrine and metabolism division, Department of Medicine, King Chulalongkorm Memorial Hosptial