Newly diagnosed acute myeloid leukemia aged greater than 18 years Acute myeloid leukemia, molecular, incidence, next-generation sequencing
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Thai newly diagnosed AML patients aged greater than 18 years who signed consent in Protocol title The newly diagnosed acute myeloid leukemia registry and ribonucleic acid (RNA) and deoxyribonucleic acid (DNA) sample collections for further investigating about molecular mutations: Protocol number 793/2560(EC2) and had extracted DNA and RNA samples
Exclusion criteria
Exclusion criteria: 1. A patient who has poor extracted DNA quality
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of molecular mutations in Thai adult newly diagnosed AML patients by NGS technique 1 year next-generation sequencing (targeted gene sequencing: Illumina machine) | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the clinical outcome in Thai adult AML patients considering molecular mutations 1 year case record form comparing with genetic results by Illumina machine | — |
Countries
Thailand
Contacts
Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University