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A study of incidence of molecular mutations in newly diagnosed acute myeloid leukemia (AML) patients by Next-generation sequencing technique

A study of incidence of molecular mutations in newly diagnosed acute myeloid leukemia (AML) patients by Next-generation sequencing technique

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20190227003
Enrollment
139
Registered
2019-02-27
Start date
2019-03-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Newly diagnosed acute myeloid leukemia aged greater than 18 years Acute myeloid leukemia, molecular, incidence, next-generation sequencing

Interventions

Thai newly diagnosed AML patients aged greater than 18 years who signed consent in Protocol title The newly diagnosed acute myeloid leukemia registry and ribonucleic acid (RNA) and deoxyribonucleic ac
Diagnostic
Newly diagnosed acute myeloid leukemia patients treating at Siriraj Hospital

Sponsors

The organization takes responsibility for initiating a study.
Lead Sponsor
The organization takes responsibility for managing a study.
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: Thai newly diagnosed AML patients aged greater than 18 years who signed consent in Protocol title The newly diagnosed acute myeloid leukemia registry and ribonucleic acid (RNA) and deoxyribonucleic acid (DNA) sample collections for further investigating about molecular mutations: Protocol number 793/2560(EC2) and had extracted DNA and RNA samples

Exclusion criteria

Exclusion criteria: 1. A patient who has poor extracted DNA quality

Design outcomes

Primary

MeasureTime frame
incidence of molecular mutations in Thai adult newly diagnosed AML patients by NGS technique 1 year next-generation sequencing (targeted gene sequencing: Illumina machine)

Secondary

MeasureTime frame
To evaluate the clinical outcome in Thai adult AML patients considering molecular mutations 1 year case record form comparing with genetic results by Illumina machine

Countries

Thailand

Contacts

Public ContactWeerapat Owattanapanich

Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University

weerapato36733@gmail.com0891081983

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026