Skip to content

Role of Oral Iron Supplementation in Treatment of Anemia Secondary to Acute Nonvariceal Upper Gastrointestinal Bleeding: A Randomized Controlled Trial

Role of oral iron supplement in non-variceal upper gastrointestinal bleeding

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20190225002
Enrollment
168
Registered
2019-02-25
Start date
2019-03-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

non variceal upper gastrointestinal bleeding oral iron supplement, anemia, non variceal upper gastrointestinal bleeding

Interventions

Ferrous fumarate (200 mg/tab) three times per day for 6 week after episode of upper gastrointestinal bleeding,no intervention
Experimental Drug,No Intervention No treatment
iron supplement,control group

Sponsors

Hatyai Hospital Foundation
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. non variceal upper gastrointestinal bleeding who admited in hospital 2. age between 18-75 years 3. who was diagnosed with anemia secondary to UGIB on the day of inclusion (Anemia was defined according to the definitions of the World Health Organization (WHO): hemoglobin level lower than 12 g/dL for women and 13 g/dL for men)

Exclusion criteria

Exclusion criteria: (1) pregnant or nursing mothers (2) pathologies that could influence anemia progression (including chronic renal failure, decompensated cirrhosis, cancer, presence of systemic inflammatory response syndrome [SIRS] or sepsis) (3) history of overt UGIB within 3 months prior to inclusion (4) previous iron supplementation intake within 3 months (5) history of chronic anemia or treatment of erythropoietin (6) contraindication of iron use (e.g., hemochromatosis, thalassemia major, and history of allergy to oral iron medicine)

Design outcomes

Primary

MeasureTime frame
Serum hemoglobin level 6 week after upper gastrointestinal bleeding g/dL

Secondary

MeasureTime frame
serum iron 6 week after upper gastrointestinal bleeding microgram/dL,TIBC 6 week after upper gastrointestinal bleeding microgram/dL,Serum ferritin 6 week after upper gastrointestinal bleeding nanogram/dL,adverse drugs reaction of iron supplement 6 week after upper gastrointestinal bleeding times

Countries

Thailand

Contacts

Public ContactArunchai Change

Hatyai Hospital

busmdcu58@gmail.com0650979414

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026