hemodynamic (heart rate,
Conditions
Interventions
check the anesthetic efficiency of 2% mepivacaine with 1:100000 epinephrine,check the anesthetic efficiency of 3% mepivacaine with 1:100000 epinephrine and compare it with 2% mepivacaine
Diagnostic,Diagnostic
inferior alveolar nerve block,inferior alveolar nerve block
Sponsors
None listed
Eligibility
Sex/Gender
All
Age
18 Years to 37 Years
Inclusion criteria
Inclusion criteria: 1. Bilateral impacted lower third molars that required flap opening, bone removal and tooth sectioning during the intervention. 2. No signs or symptoms of infection or inflammation at the lower third molar areas. 3. Patient has a good health with the absence of any systemic condition. 4. The patient is not taking any medication which would affect the pain perception. 5. The patient is able to understand and fulfill the investigator’s instructions.
Exclusion criteria
Exclusion criteria: 1. The patient has medical history of any systemic disease 2. Allergy to the local anesthetic agents or nonsteroidal anti-inflammatory drugs 3. Pregnancy or current lactation patient 4. The patient with facial deformities which might intervene local anesthetic administration, surgery, or future investigations 5. The presence of an infection or inflammation at the lower third molar sites 6. Any drug intake 7. The patient in unable to follow the investigator’s instructions or cooperate during the study period
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Onset and duration of anesthesia 205.88±35.36 minutes starting of numbness of the lip until the sensation is back to normal (using a stop watch),hemodynamic considerations 30 minutes heart rate and blood pressure monitoring devices | — |
Secondary
| Measure | Time frame |
|---|---|
| pain 25 minutes patient report (using the VAS scores),duration of postoperative anesthesia 170 minutes (approximately) patient report (lip numbness is gone, sensation is back to normal (using a stop watch),pulp vitality 15 minutes Electrical Pulp test device | — |
Countries
Thailand
Contacts
Public ContactNatthamet Wongsirichat
Faculty of Dentistry, Mahidol University
Outcome results
None listed