Hemodynamic Response of Dexmedetomidine versus Additional Intravenous Lidocaine with Propofol during Tracheal Intubation. Dexmedetomidine,
Conditions
Interventions
1.5 mg/kg of lidocaine in 10 ml of normal saline over 3 minutes before induction and an additional dose of propofol (0.5 mg/kg) 60 seconds after the rocuronium administration.,1 mcg/kg of dexmedetomid
Experimental Drug,Active Comparator Drug
Additional Intravenous Lidocaine with Propofol,Dexmedetomidine
Sponsors
Faculty of Medicine Ramathibodi Hospital, Mahidol University
Department of Anesthesiology
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Aged between 18-65 years ASA physical status I-II undergo elective surgery under general anesthesia Weighing between 40 – 80 kg BMI between 18 – 24.99 kg/m2 Mallampati Classification grade I - II
Exclusion criteria
Exclusion criteria: Patient with coronary artery disease and cerebrovascular disease Hypertension Pregnancy Emergency surgery Full stomach
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| systolic, diastolic, mean arterial blood pressure, heart rate at preinduction, one minute after induction, two minute after induction, intubation phase, one minut mmHg, per minute | — |
Secondary
| Measure | Time frame |
|---|---|
| Complication: hypotension, bradycardia at the end of intervention number and percentage | — |
Countries
Thailand
Contacts
Public ContactChusak Okascharoen
Ramathibodi Hospital Mahidol University
Outcome results
None listed