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The effect of caspase inhibitor on human cumulus cell viability in vitrification-thaw cycles : a single-blind randomized controlled trial

The effect of caspase inhibitor on human cumulus cell viability in vitrification-thaw cycles : a single-blind randomized controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20190202001
Enrollment
Unknown
Registered
2019-02-02
Start date
2018-11-22
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cumulus cells caspase inhibitor apoptosis germinal vesical

Interventions

no intervention,vitrified cumulus cell without caspase inhibitor ,vitrified cumulus cell with caspase inhibitor in DMSO 60 uM
No Intervention Biological/Vaccine,Experimental Biological/Vaccine,Experimental Biological/Vaccine
fresh cumulus cells,vitrified cumulus cells without caspase inhibitor,vitrified cumulus with caspase inhibitor

Sponsors

siriraj research fund
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 37 Years

Inclusion criteria

Inclusion criteria: infertile women who indicated for IVF treatment had appointment for oocyte retreival age 18-37 years old

Exclusion criteria

Exclusion criteria: women who not allow to use their cumulus cells

Design outcomes

Primary

MeasureTime frame
The apoptotic rate of vitrified cumulus cells between with and without caspase inhibitor 7 days TUNEL assay—

Secondary

MeasureTime frame
The apoptotic rateof cumulus cells between vitrified cumulus cells with caspase inhibitor and fresh 7 days TUNEL assay—

Countries

Thailand

Contacts

Public Contactchompunut chantragawee

obstretics and gynaecology department, siriraj hospital

chompunut059@gmail.com0875107876

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026