Comparison of glucose control by added liraglutide to only insulin infusion in DM patient undergoing cardiac surgery: A randomized-controlled trial

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

TCTR

Registry ID

TCTR20190118012

Enrollment

Registered

2019-01-18

Start date

2018-05-01

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Glycemic variability in diabetic patients who undergo the cardiac surgery Glycemic Variability: GV = Coefficient of variation = standard deviation/mean Liraglutide Drug = VictozaTM Continuous glucose monitoring = IPro2

Interventions

Use Liraglutide drug for preoperative(1 day before surgery)&#44

intraoperative(day of surgery) and postoperative(3 days after surgery) periods. The patients use insulin drug for blood glucose control in that period likes standard treatment.,The patients use insuli

intraoperative and postoperative periods likes standard treatment.

Experimental Drug,Active Comparator Drug

Liraglutide added with insulin on blood glucose control in Cardiac Surgery ,Insulin on blood glucose control in Cardiac patients

Eligibility

Sex/Gender

All

Age

20 Years to 85 Years

Inclusion criteria

Inclusion criteria: Diabetic patients who undergo coronary artery bypass graft operation or valvular surgery that use cardiopulmonary bypass

Exclusion criteria

Exclusion criteria: 1.History allergy to Liraglutide or insulin drug 2.Patients have contraindication for using Liraglutide drug such as Medullary thyroid carcinoma, Multiple Endocrine Neoplasia Syndrome type2(MEN type2), Thyroid C-cell tumors and Pancreatitis 3.Patients have Diabetic Ketoacidosis condition during reseach progression. 4.Patientds have allergic reaction to liraglutide drug during reseach progression.

Design outcomes

Primary

Measure	Time frame
The effect of Liraglutide on glycemic variability in cardiac surgery Intraoperative and Postoperative periods Glycemic Variability = Coefficient of variation = standard deviation/mean glucose level of patients	—

Secondary

Measure	Time frame
Effect of Liraglutide for reduction of insulin usage on blood glucose control in cardiac surgery Intraoperative and Postoperative periods Evalutation dose of insulin usage between Liraglutide added with insulin and insulin only groups	—

Countries

Thailand

Contacts

Public ContactWeerasake Poopuangpairoj

unaffiliation

weesi111@hotmail.com66856185541

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026

Comparison of glucose control by added liraglutide to only insulin infusion in DM patient undergoing cardiac surgery: A randomized&#45;controlled trial