Lidocaine efficacy still controversy Intravenous lidocaine,
Conditions
Interventions
Lidocaine 1.5 mg/kg upto 10 ml bolus
then Lidocaine 2 mg/kg/hr. upto 20 ml Infusion volume rate 20 ml/hr.
in surgery and 1 hr after surgery ,same volume of NSS
Experimental Drug,Placebo Comparator No treatment
Lidocaine,saline
Sponsors
Srinakharinwirot university
Srinakharinwirot university
Eligibility
Sex/Gender
Female
Age
30 Years to 65 Years
Inclusion criteria
Inclusion criteria: Female patients Aged 30-65 years BMI < 35 kg/m2 American Society of Anesthesiologists (ASA) physical status I or II Scheduled for elective abdominal hysterectomy with general anesthesia.
Exclusion criteria
Exclusion criteria: Unable to use IV-PCA History of allergy to local anesthetics Severe cardiovascular, respiratory, renal or hepatic disease History of seizure Severe psychiatric medical history Preoperative opioids medication and substance abuse Chronic pain syndromes
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Morphine Consumption 48 hrs. total dose of morphine that patients press | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain Score 24 hours visual analog scale | — |
Countries
thailand
Contacts
Public ContactRattanaporn Imarom
Department of Anesthesiology, Faculty of Medicine, HRH Princess Maha Chakri Sirindhorn Medical Cente
Outcome results
None listed