Acne Vulgaris Post Acne Hyperpigmentation Acne Vulgaris Post Acne Hyperpigmentation
Conditions
Interventions
Jessner’s Solution is a chemical containing salicylic acid,
lactic acid and resorcinol that has been used in the market for decades,
especially in the field of dermatology and aesthetic.,Salicylic acid had been known to be lipophilic and had anti-
inflammatory properties. Its efficacy in the treatment of acne vulgaris is well established
Experimental Device,Active Comparator Device
Jessner'
s Solution,Salicylic Acid 30%
Sponsors
Dermatological Society of Malaysia
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1. Males and females with acne vulgaris aged ≥ 18 years old 2. Should have at least 10 inflammatory AND/ OR non-inflammatory lesions at each side of the face 3. Have acne for more than 6 months
Exclusion criteria
Exclusion criteria: 1. Other forms of acne (acne conglobata, acne excoriate, acne rosacea, acne cosmetica, pomade acne, acne fulminans, acne keloidalis nuchae, acne chloracne, acne mechanica and acne medicamentosa) 2. Nodulocystic acne 3. On oral antibiotic for the last 1 months 4. On oral isotretinoin for the last 6 months 5. On topical antimicrobial or tretinoin for the last 2 weeks 6. Photosensitivity 7. Recent (2-6months) facial undermining surgery (blepharoplasty, rhytidectomy, brow lift, liposuction) in the treatment area 8. If there is any active or past infection, such as HSV, herpes zoster infection 9. If there is any active bacterial folliculitis at this moment 10. History of keloid 11. Poor skin turgor 12. If patient is currently pregnant or lactating 13. Other comorbidities, especially immunocompromising diseases (possibility of dealy healing, increased susceptibility to infection, or excessive pigmentation after peeling) 14. If there is any known allergy to the active ingredients in the preparation 15. Patients who have any other dermatoses, especially facial dermatoses 16. Patients who like outdoor activities and couldn’t comply to sunprotection. 17. Fitzpatrick skin type I-II 18. Patients who had a difference of 2 grades or above, comparing one side of the face to another.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in total number of inflammatory lesions and non-inflammatory lesions. At each clinic visit lesions count | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in the Michaelson Acne Score (MAS) At each clinic visit Michaelsson Acne Score,Changes in post acne hyperpigmentation index (PAHPI) at each clinic visit PAHPI,The patient’s satisfactory rate towards the treatment Last clinic visit Visual Analogue Scale,The frequency of overall all adverse reaction towards the treatment At each clinic visit Frequency | — |
Countries
Malaysia
Contacts
Public ContactKang Nien How
Faculty of Medicine and Health Sciences, Universiti Putra Malaysia
Outcome results
None listed