ascariasis hookworm infection trichuriasis strongyloidiasis anthelmintics albendazole mebendazole ivermectin ascariasis hookworm infection trichuriasis strongyloidiasis
Conditions
Interventions
Albendazole 400 mg single dose,Albendazole 400 mg twice daily for 3 days,Ivermectin 200 ug/kg single dose,Mebendazole 100 mg twice daily for 3 days,Albendazole 400 mg single dose combined with Ivermec
Active Comparator Drug,Experimental Drug,Experimental Drug,Experimental Drug,Experimental Drug,Experimental Drug
ABZ single dose,ABZ triple dose,IVR single dose,MBZ triple dose,ABZ+IVR,MBZ+IVR
Sponsors
Department of Parasitology, Faculty of Medicine, Chulalongkorn University
Thai One Health Network,
Thailand MOPH -
U.S. CDC Collaboration
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) Age: 18-70 years old. 2) infected with any of the four species of STHs (i.e. Ascaris or hookworms or Trichuris or Strongyloides).
Exclusion criteria
Exclusion criteria: 1) history of acute or severe chronic. 2) pregnancy or lactation 3) vomit within 4 hours after drug administration. 4) unable to provide a stool sample at follow-up. 5) known history of allergic reaction to ABZ, MBZ, IVR.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cure rate 3 wks after treatment Modified Kato-Katz thick smear,Harada-mori culture | — |
Secondary
| Measure | Time frame |
|---|---|
| egg reduction rate (ERR) 3 wks after treatment Modified Kato-Katz thick smear, Harada-mori culture | — |
Countries
Thailand
Contacts
Public ContactVivornpun Sanprasert
Department of Parasitology, Faculty of Medicine, Chulalongkorn University
Outcome results
None listed