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Osseointegration of Maxillary Dental Implants in Diabetes Mellitus Patients: A Human Histomorphometric Study

Osseointegration of Maxillary Dental Implants in Diabetes Mellitus Patients: A Human Histomorphometric Study

Status
Recruiting
Phases
Phase 1
Study type
Observational
Source
TCTR
Registry ID
TCTR20190103004
Enrollment
Unknown
Registered
2019-01-03
Start date
2018-09-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes mellitus Osseointegration of dental implant and bone implant contact calculation bone to implant contact dental implants healing around dental implants insulin resistance type 2 diabetes mellitus

Interventions

type 2 diabetes patients with or without taking medications&#44
no cardiovascular complications and have HbA1c no more than 8%,non diabetes group with normal level of fasting plasma glucose
Other,Other
controlled Type 2 diabetes mellitus,Healthy control

Sponsors

Faculty of Dentistry
Lead Sponsor
Center of Excellence for Dental Implantology
Collaborator

Eligibility

Sex/Gender
All
Age
20 Years to 65 Years

Inclusion criteria

Inclusion criteria: type 2 diabetes for test group Physically healthy (ASA I or II classification) Psychological and emotional stable No history of bone fracture during the last 12 months Tooth loss at upper premolar or molar area (at least 6 months removal) & seek dental implant placement Sufficient keratinized gingival at least 4 mm Alveolar bone width of at least 6 mm and height of 12 mm (by CBCT) No bone augmentation procedure needed before and during implant placement Stable dental occlusion

Exclusion criteria

Exclusion criteria: Pregnant or lactating females Use of anti-inflammatory and immunosuppressive drugs HIV Current smoking or ex-smoker Patients with major complications of Diabetes (Cardiovascular and peripheral vascular disease, neuropathy and nephropathy) History of chemotherapy or radiotherapy around head and neck area Third molar and anterior edentulous area

Design outcomes

Primary

MeasureTime frame
Bone implant contact two months after micro implant placement bone histomorphometry

Secondary

MeasureTime frame
dental implant stability after conventional implant placement Implant stability quotient (ISQ) measurement

Countries

Thailand

Contacts

Public ContactPathawee Khongkhunthian

Center of Excellence for Dental Implantology

pathaweek@gmail.com+66818840688

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026