Efficacy of Non-pharmacological Intervention Protocol in Reducing the Incidence of Postoperative Delirium in Elderly Patients Admitted to Surgical Intensive Care Units

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

TCTR

Registry ID

TCTR20181201001

Enrollment

300

Registered

2018-12-01

Start date

2018-06-04

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Delirium Postoperative Delirium Non-pharmacological

Interventions

This study is a quasi&#45

experimental before&#45

and&#45

after design. The eligible patients will be enrolled following the inclusion criteria and excluded by exclusion criteria. Those patients will be allocated into standard of cares group (pre cohort) and

all of the process of care is based on the discretion of the responsible attending staffs. In the POST cohort&#44

the non&#45

pharmacological intervention protocols are implemented to all patients once they are admitted to the SICU and continued for 28 consecutive days or until they are discharged from the SICU or death. In

delirium is screened using the Thai&#45

version Confusion Assessment Method for the ICU (CAM&#45

ICU) by well&#45

trained research assistances twice a day between 08:00 to 10:00 and 18:00 to 20:00. The screening is carried out within 24 hours after SICU admission. In case of positive CAM&#45

ICU&#44

delirium is diagnosed and subsequently classiï¬ed as hyperactive&#44

hypoactive&#44

or mixed types. In the PRE cohort&#44

delirious patients are managed based on the discretion of the attending staffs. In the POST cohort&#44

delirious patients are managed according to the pharmacological protocol initiated by trained attending staffs&#44

SICU fellows and residents.

Experimental Behavioral

Non&#45

Eligibility

Sex/Gender

All

Age

65 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1.Age of 65 years old or more 2.Admitted to two SICUs at Siriraj hospital within seven days following surgery 3.Anticipated LOS in SICU of more than 24 hours.

Exclusion criteria

Exclusion criteria: 1.Patients undergoing surgery for more than seven days 2.Non-surgical patients 3.Patients who cannot communicate in Thai language 4.Patients with severe visual and auditory impairment that preclude communication

Design outcomes

Primary

Measure	Time frame
Postoperative delirium at 28 consecutive days or until they are discharged from the SICU or death non-pharmacological intervention protocol	—

Secondary

Measure	Time frame
Delirium free day at 28 consecutive days or until they are discharged from the SICU or death non-pharmacological intervention protocol	—

Countries

Thailand

Contacts

Public ContactAnnop Piriyapatsom

Mahidol university

annop.pir@mahidol.ac.th0922819241

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026