Skip to content

Effect of calcium hydroxide mixed with Lidocaine hydrochloride on postoperative pain in teeth with irreversible pulpitis and symptomatic apical periodontitis: a preliminary randomized controlled prospective clinical trial

Effect of calcium hydroxide mixed with Lidocaine hydrochloride on postoperative pain in teeth with irreversible pulpitis and symptomatic apical periodontitis: a preliminary randomized controlled prospective clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20181121003
Enrollment
Unknown
Registered
2018-11-21
Start date
2018-10-04
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sixty patients having irreversible pulpitis and symptomatic apical periodontitis with a preoperative and percussion pain of visual analog scale (VAS) more than 50 were included apical periodontitis&#44

Interventions

calcium hydroxide mixed with saline,calcium hydroxide mixed with Lidocaine HCl
control group ,calcium hydroxide mixed with Lidocaine HCl

Sponsors

no
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Mandibular molar teeth that were diagnosed with irreversible pulpitis [prolonged pain to cold test (Roeko Endo-Frost spray; Coltene Whaladent, Langenau, Germany)] and symptomatic apical periodontitis (percussion pain), 2. Patients with preoperative spontaneous or percussion pain level equal or above 50 mm on VAS scale, 3. Patients who have no systemic disease and older than 18 years old, 4. Teeth with PAI scores 1 and 2 described by Qrstavik et al.

Exclusion criteria

Exclusion criteria: 1. Presence of sinus tract or swelling with associated tooth, 2. Teeth which haven’t occlusion with the opposite tooth, 3. The presence of periodontal pockets more than 3 mm in the associated tooth, 4. Severely damaged teeth, 5. Teeth with root resorption, root fracture or ankylosis. 6. Teeth with previous root canal treatment, 7. Patients who have psychiatric disorders, systemic diseases or allergic reactions, 8. Pregnant patients, 9. Patients who were older than 65 years old, 10. Patients who have parafunctional habits such as bruxism.

Design outcomes

Primary

MeasureTime frame
Pain 1 week VAS

Secondary

MeasureTime frame
Postoperative percussion pain 1 week VAS

Countries

Turkey

Contacts

Public ContactHakan Arslan

Ataturk University

dt_hakan82@hotmail.com05339351238

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026