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EFFECT OF TOPICAL FLUORIDE ON INCIPIENT CARIOUS LESIONS: RANDOMIZED CLINICAL TRIAL

EFFECT OF TOPICAL FLUORIDE ON INCIPIENT CARIOUS LESIONS: RANDOMIZED CLINICAL TRIAL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20181115014
Enrollment
Unknown
Registered
2018-11-15
Start date
2017-05-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

actively incipient carious lesion on permanent upper incisor teeth supervised tooth brushing Sodium Fluoride Mouthrinse Sodium Fluoride Varnish Remineralization Incipient carious lesion

Interventions

Brush their teeth after lunch with 1000 ppm fluoride toothpaste under the supervision of school’s hygienic teacher. Children were advised not to eat any food or beverages for 30 minutes after brushi
supervised tooth brushing,fluoride mouthrinse,fluoride varnish,control

Sponsors

Faculty of Dentistry, Chulalongkorn University
Lead Sponsor
Faculty of Dentistry&#44
Collaborator
Chulalongkorn University
Collaborator

Eligibility

Sex/Gender
All
Age
10 Years to 12 Years

Inclusion criteria

Inclusion criteria: All participants had two active incipient carious lesions on permanent upper central incisor teeth.

Exclusion criteria

Exclusion criteria: They had no history of systemic disease, congenital, physical or mental disability and never used any medications which altered salivary flow/composition. All participants brush their teeth with fluoride toothpaste twice a day. They have not received any topical fluoride therapy in the last six months.

Design outcomes

Primary

MeasureTime frame
Activity of incipient carious lesion 6 month tactile sense with blunt explorer

Secondary

MeasureTime frame
Lesion size 6 month digital images

Countries

Thailand

Contacts

Public ContactChananuch Chanpanya

Faculty of Dentistry, Chulalongkorn University

chananuch_belle@hotmail.com0911209668

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026