Severe hypoglycemia Severe neuroglycopenic symptoms Respond after IV 50% glucose bolus
Conditions
Interventions
Continuous IV dextrose after 50% glucose bolus until blood glucose stable. Others as usual.,Let the patients have meals after 50% glucose bolus until blood glucose stable. No IV fluid containing dextr
IV dextrose,Meals
Sponsors
Emergency unit Chulalongkorn hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients visit emergency room at King chulalongkorn memorial hospital KCMH age between 18-70 years who meet the following criteria 1 The patients with all type of diabetes mellitus 2 POCT glucose at triage less than 70 mg% 3 Severe hypoglycemia with autonomic symptom and/or neuroglycopenic symptom 4 Patients who meet the criteria of severe hypoglycemia 5 Fully recovery after 50% glucose bolus to GCS 15 and understand the research methods 6 Can tolerate oral meals
Exclusion criteria
Exclusion criteria: 1 Patient whose symptoms doesn't resolve after 50% glucose bolus and the POCT glucose return to normal range 2 Patient who cannot understand the research methods 3 Pregnancy, lactation 4 Hypoglycemia from overdose 5 History of endocrine tumor or malignancy 6 Cannot tolerate oral meals 7 Suspected of more severe disease and/or have to admit to hospital 8 Patients who recently took steroids 9 Fluid restricted patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hypoglycemia event 1 day POCT glucose in each time | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to hypoglycemia event 1 day Time,Other factors leads to hypoglycemia event during intervention period 1 day Catagorical outcome | — |
Countries
Thailand
Contacts
Public ContactPakhawadee Palungwachira
Chulalongkorn hospital
Outcome results
None listed