Healthy Thai female subjects Anti aging skin irritation patch test
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: - Healthy female age 30-60 years - Having combination to oily skin - Having clear visible wrinkle at eye corners (crow's feet) and fore head - Having experience using a counter brand facial skin care - No wound, scar or any dermatological disorders on the volar forearm - No smoking, alcoholic and drug addiction - No history of allergic problem to commercially available anti-wrinkle products - Having willingness to cooperate with the project and be able to follow the study protocol - Willing to give a written consent of the volunteer - Be able to read, communicate and write Thai language
Exclusion criteria
Exclusion criteria: - History of hyper allergic skin reaction to any cosmetic products - History of skin eczema, psoriasis, within 6 months before enter the study - History of using steroid, antibiotic and antihistamine within 3 days before enter the study - History of using topical medicine on the face within 3 weeks before enter the study - Having chronic diseases and taking medicines - History of major operation during the last year - History of skin cancer during the last year - Pregnancy and lactation - Having scar on the evaluation area
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin irritation and safety of cosmetic products 24 hours 24 hours patch test,Skin hydration Week 0, 1, 4 , 8 corneometer,Skin elasticity Week 0, 1, 4 , 8 Cutometer,Skin roughness and wrinkle Week 0, 1, 4 , 8 Visioscan and Visia,self assessment Week8 satisfaction questionnaire | — |
Secondary
| Measure | Time frame |
|---|---|
| N/A N/A N/A | — |
Countries
Thailand
Contacts
Cosmetics and natural products research center, Faculty of Pharmaceutical Sciences, NU