Healthy Thai female subjects Whitening Skin moisturizer Efficacy test Lightening effect
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: - Healthy volunteers with an age in a range of 25-35 years old - Having dull skin, pigmentary dark spots on the face - Having experience using counter brand - No history of allergic againts any components of trial products or whitening cosmetics - Be able to use only provide products and no other similar products (exeception for their normal products in the other categories according to their routine habits) during the test period - No functional supplements which improve skin condition or no treatment prior the clinical test for 1 month - Be able to follow the study protocol - Willing to give consent of the volunteer
Exclusion criteria
Exclusion criteria: - History of hyper allergies against any components of trial products or whitening cosmetics - History of skin eczema psoriasis within 6 months before enter the study - History of herpes - Facial warts, wounds or scars - Medical or cosmetic treatment with steroids, antibiotics, NSAIDS, antihistamine, AHAs, azelic acid, kojic acid, hydroquinone, chemical peels, tretinion or isotretinion within weeks before the study - History of major operation within 1 year -History of skin cancer within 1 year -Smoker and/or heavy alcohol drinker and/or narcotic user - Pregnancy and lactation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin moisturizing effect Week 0, 1, 4 , 8 Using corneometer,Quantification of the lightening effect Week 0, 1, 4 , 8 Using chromameter,Melanin index and erythma value Week 0, 1, 4 , 8 Using maxameter,Visual evaluation Week 0, 1, 4 , 8 Using VISIA,Self assessment Week 0, 1, 4 , 8 Satisfaction questionnaire | — |
Secondary
| Measure | Time frame |
|---|---|
| N/A N/A N/A | — |
Countries
Thailand
Contacts
Cosmetics and natural products research center, Faculty of Pharmaceutical Sciences, NU