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Warning signs for severe dengue and clinical manifestations of different dengue serotype infection in adolescent and adult Thai patients

Warning signs for severe dengue and clinical manifestations of different dengue serotype infection in adolescent and adult Thai patients

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20181110001
Enrollment
400
Registered
2018-11-10
Start date
2017-02-28
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dengue infection dengue warning signs of severe dengue

Interventions

Thai adults and adolescences with dengue infection
Diagnostic
dengue

Sponsors

Mahidol University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Thai male and female 2. Age ≥ 15 years 3. Fever not more than 5 days 4. Willing to participate&#44; written informed consent be obtained. In case of age < 18 years&#44; parents written informed consent also be obtained 5. Laboratory confirmation of dengue infection by at least one of the followings: • Positive dengue NS1 antigen • Positive dengue IgM • Seroconversion of dengue IgG

Exclusion criteria

Exclusion criteria: 1. Coinfection 2. Pregnancy

Design outcomes

Primary

MeasureTime frame
dengue severity 2 weeks after enrollment WHO 1997 and 2009 dengue classification

Secondary

MeasureTime frame
clinical characteristics of patients infected with different dengue serotypes at the end of the study history taking&#44; physical examination and laboratory investigation,factors affecting warning signs and severity of dengue&#45;infected patients at the end of the study history taking&#44; physical examination and laboratory investigation

Countries

Thailand

Contacts

Public ContactBorimas Hanboonkunupakarn
borimas.han@mahidol.edu02-354-9168

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026