postmenopause presarcopenia vitamin D estrogen testosterone postmenopausal women menopause presarcopenia muscle mass muscle strength estrogen androgen vitamin D
Conditions
Interventions
Sponsors
Ratchadapiseksompoj Research Fund
Eligibility
Sex/Gender
Female
Age
45 Years to 65 Years
Inclusion criteria
Inclusion criteria: women age 45 - 65 years old women who has been amenorrhea at least 12 months willing to participate
Exclusion criteria
Exclusion criteria: women who need caretaker women who cannot walk women who cannot measure hand grip strength History of chronic diseases such as; renal failure, stroke, lung disease, heart failure, cancer History of thyroid disease History of myopathy History of abnormal parathyroid function history of bone or joint surgery within 2 years History of hospitalization at least 7 days within 3 months Women who has taken vitamin D supplement within 12 months History of steroid use within 3 months Women who has metal devices in the body
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Muscle mass first visit kg/m2/ weight by Bioelectrical impedance analysis,muscle strength first visit kg/ hand grip strength,muscle strength first visit kg/ hand grip strength,muscle strength first visit kg/ hand grip strength,muscle strength first visit kg/ hand grip strength,muscle effectiveness first visit m/sec/ Gait speed | — |
Secondary
| Measure | Time frame |
|---|---|
| estradiol First visit pg/ml/ blood test,free anrogen index (FAI) First visit rato/blood test,25OHD First visit ng/ml/ blod test | — |
Countries
Thailand
Contacts
Public ContactSukanya Chaikittisilpa
Faculty of Medicine, Chulalongkorn University
Outcome results
None listed