recovery of neurosensory disturbance after Bilateral Sagittal Split Ramus Osteotomy. vitamin B orthognathic surgery nerve injury neurosensory disturbance
Conditions
Interventions
Each patient will be prescribed vitamin B1-
12 (SAMBEE® tablet) as 1 tab tid pc after BSSRO for 6 months. ,Each patient will be prescribed vitamin B 12 (Methylcobal® 500 mg tablet) as 1 tab tid pc after BSSRO for 6 months. ,Each patient will
Active Comparator Dietary Supplement,Active Comparator Dietary Supplement,No Intervention Dietary Supplement
vitamin B1-
12 ,vitamin B12,Control
Sponsors
Chulalongkorn University
Eligibility
Sex/Gender
All
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1.BSSRO procedure with or without maxillary procedure (without genioplasty) and have reduced sensation after surgery (GSS≤12) 2.Aged between 20-50 years 3.Healthy patient, no medical problems 4.No numbness or unusual feeling on the face before surgery 5.No psychological problems 6.No infection problems 7.No sensitivity to vitamin B
Exclusion criteria
Exclusion criteria: 1.Perioperative complications such as bone exposed, partial or complete nerve dissection, excessive bleeding or unfavorable bone fracture 2.Postoperative complications such as postoperative infection, the operation that need second operation (for example: broken bur) 3.Patient with postoperative dysesthesia that need microneurosurgery 4.Patient who receive other medication that influence nerve healing 5.Patient lost follow-up in 6 months after surgery 6.Non co-operative patients
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The recovery of neurosensory disturbance immediately, 1 week, 1 month, 3 months and 6 months after BSSRO Clinical Neurosensory Test with static and moving 2 point discrimination, light touch and pinprick | — |
Secondary
| Measure | Time frame |
|---|---|
| Quality of life of patients immediately, 1 week, 1 months, 3 months and 6 months after BSSRO Questionaire | — |
Countries
Thailand
Contacts
Public ContactPaksinee Kamolratanakul
Department of Oral and Maxillofacial Surgery
Outcome results
None listed