Skip to content

The mineral density of proximal artificial caries lesions was increased by 1500 ppm fluoride dentifrice compared with 1000 ppm fluoride dentifrice in situ

The mineral density of proximal artificial caries lesions was increased by 1500 ppm fluoride dentifrice compared with 1000 ppm fluoride dentifrice in situ

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
TCTR
Registry ID
TCTR20181018002
Enrollment
Unknown
Registered
2018-10-18
Start date
2015-07-07
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Proximal artificial enamel caries lesions in high caries risk patients.

Interventions

The study consisted of two experimental phases with a one week wash out period between each phase. The volunteers were randomly allocated into two fluoride product regimens: brushing with 1000 ppmF&#4
dentifrice 2x day with a one week 1000 ppmF&#45
toothpaste use washout period between each phase,The study consisted of two experimental phases with a one week wash out period between each phase. The volunteers were randomly allocated into two fluo
dentifrice 2x day&#44
with a one week 1000 ppmF&#45
toothpaste use washout period between each phase
Experimental Procedure/Surgery,Experimental Procedure/Surgery
1000 ppmF&#45
dentifrice,1500 ppmF&#45

Sponsors

Dental Research Fund, Dental Research Project, Faculty of Dentistry, Chulalongkorn University.
Lead Sponsor
Faculty of Dentistry&#44
Collaborator
Chulalongkorn University.
Collaborator

Eligibility

Sex/Gender
All
Age
19 Years to 23 Years

Inclusion criteria

Inclusion criteria: - high caries risk as determined by the criteria of ADA caries risk assessment form 2016. - at least 22 natural teeth with no current caries activity, periodontal disease, or other oral pathology. - had an unstimulated salivary flow rate of ≥ 0.1ml/min.

Exclusion criteria

Exclusion criteria: - not high caries risk patient - has less than 22 teeth

Design outcomes

Primary

MeasureTime frame
mineral density 2 Phase (Pre and Post intervention) MicroCT

Secondary

MeasureTime frame
depth change 2 Phase (Pre and Post intervention) MicroCT

Countries

Thailand

Contacts

Public ContactKunanond Pongsakornvanich

Department of Pediatric Dentistry, Faculty of Dentistry, Chulalongkorn University

kunanond.p@gmail.com081-4465977

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026