Comparison of efficacy between Nefopam and Placebo for prevention of shivering during spinal anesthesia in patient undergoing cesarean section nefopam shivering prevention spinal anesthesia ceasarean section
Conditions
Interventions
20mg of nefopam in normal saline upto 100 ml intravenous drip in 30 min after the baby was delivered,100 ml of normal saline intravenous drip in 30 min after the baby was delivered
Experimental Drug,Placebo Comparator No treatment
Sponsors
Research affairs Faculty of medicine,Chulalongkorn University
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: pregnant woman gestrational age 36-42 weeks who undergoing cesarean section under spinal anesthesia the american society of anesthesiologists physical status II-III
Exclusion criteria
Exclusion criteria: -patients who have abnormal function of thyroid, heart, lungs, neurological function -patients who have muscle disease or history of malignant hyperthermia -patients who have phychological problems -patients who have a fever perioperative(body temperature more than 37.5C)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Shivering 1 hr Shivering score | — |
Secondary
| Measure | Time frame |
|---|---|
| comparison of Hemodynamic between nefopam group and placebo group 6, 12, 18 and 24 hr Heart rate, Blood pressure,complication of nefopam 6, 12, 18 and 24 hr nausea, pain on injection, respiratory depression | — |
Contacts
Public ContactSomrat Charuluxanan
Faculty of Medicine, Chulalongkorn University
Outcome results
None listed