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Two New Therapies in the Cocaine-dependents, Comparison of Topiramate and Contingency Management, a Single-center

Two New Therapies in the Cocaine-dependents, Comparison of Topiramate and Contingency Management, a Single-center Placebo-controlled Trial, Pilot Randomized

Status
Active, not recruiting
Phases
Phase 1Phase 2
Study type
Interventional
Source
TCTR
Registry ID
TCTR20180926002
Enrollment
Unknown
Registered
2018-09-26
Start date
2014-07-05
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

All stages of the research were performed after obtaining informed written consent from the parents and the verbal consent of the child and based on the latest version of Helsinki Declaration. Topiramate&#44

Interventions

In TPM group&#44
participants were received esca&#45
lating doses. In addition&#44
contingency manage&#45
ment was provided for twelve weeks. All sub&#45
jects received brief behavioral compliance en&#45
hancement treatment (BBCET). ,contingency management was provided for twelve weeks,Mix group receive topiramate and contingency management
Experimental Drug,Experimental Behavioral,Experimental Other
Topiramate ,contingency management ,Mix group

Sponsors

none
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: The inclusion criteria for participation in this study were: 1) having the respective age between 18 and 31, 2) History of one months of cocaine avoidance, and 3) having at least the educational level of Diploma.

Exclusion criteria

Exclusion criteria: Also the exclusion criteria were: 1) Report of positive urine test during remedial period, 2) Taking supplementary drug and psychological remedies, and 3) three continuous weeks of absence from participation in remedial meetings.

Design outcomes

Primary

MeasureTime frame
cocaine urine tests 8 weeks detection of benzoylecgonine

Secondary

MeasureTime frame
craving 8 weeks craving questionnaire

Countries

iran

Contacts

Public Contactbijan pirnia

Bijan Center

b.pirnia@usc.ac.ir+9802122081450

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026