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A Study of Midazolam Affects Immediate Cognitive Function in Elderly Hepatocellular Carcinoma Patients undergoing Radiofrequency Ablation

Midazolam Affects Cognitive Function in Elderly undergoing Radiofrequency Ablation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20180913004
Enrollment
Unknown
Registered
2018-09-13
Start date
2018-03-16
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Elderly Hepatocellular Carcinoma undergoing Radiofrequency Ablation. Midazolam Affects.&#44

Interventions

non midazolam group (control) ,midazolam group
Treatment,Treatment

Sponsors

Facultyof Medicine
Lead Sponsor
Siriraj Hospital
Collaborator

Eligibility

Sex/Gender
All
Age
65 Years to 80 Years

Inclusion criteria

Inclusion criteria: - Patients treated with radiofrequency ablation to destroy the tumor. The radiation treatment unit and know that they have tumors on the liver. - Patients aged 65-80 years - Patients receiving education not lower than grade 6 - Patients can communicate in listening, speaking, reading and writing. - ASA 1-3

Exclusion criteria

Exclusion criteria: - Have mental illness - Have underlying disease such as;Alzheimer's disease, dementia, neurological deficit - received the drug in the group. Antipsychotics, Regular sedative drugs - allergy to sedative agents - Preoperative neurological deficit such as Parkinson’s disease, Dementia, Vascular disease in the brain. - History of alcohol. - The function or routine of daily life is less. - Malnutrition - Elderly or very elderly. And hearing or vision defects. - Dehydration, solution and electrolyte imbalance after surgery are sodium, potassium and glucose. - Insomnia, not private location. - On Foley’s catheter. - Disorder of intellect and history of acute confusion. - Hypoxia, hypoxemia and decrease level of Hb after operative. - On Narcotic and Benzodiazepine medicine. - Uncontrol postoperative pain.

Design outcomes

Primary

MeasureTime frame
Cognitive funtions Before undergoing radiofrequency ablation MoCA test,Cognitive funtions After undergoing radiofrequency ablation MoCA test

Secondary

MeasureTime frame
N/A N/A N/A

Countries

Thailand

Contacts

Public ContactPattharaporn Sombood

Department of Anesthesiolgy, Faculty of Medicine Siriraj Hospital,Mahidol University

Pat_susai@hotmail.com0619899154

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026