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The effects of exercise or combined with diet on physical performance in middle aged obese individuals

The effects of caloric restriction in addition to exercise training on exercise capacity, muscle function and protein homeostasis in obese individuals: a translational study from animals to human

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20180913003
Enrollment
60
Registered
2018-09-13
Start date
2018-10-01
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Middle aged obese adult Obesity Exercise Caloric restriction

Interventions

Aerobic exercise ,Aerobic exercise with caloric restriction(Men:1500~1800 Kcal&#44
Women: 1200~1500 Kcal) ,No intervention
Exercise,Exercise combined with diet,Control

Sponsors

National Yang Ming University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 64 Years

Inclusion criteria

Inclusion criteria: 1. Age: 50~64 years 2. Obesity: (meet one of the three) BMI>27 Body fat%: Men≥30%&#44; Women≥35% Waist circumference: Men ≥ 90 cm&#44; Women ≥ 80 cm 3. No regular exercise habits (Moderate exercise in the past year < 150 mins/ week)

Exclusion criteria

Exclusion criteria: 1. Factors that can’t perform the exercise test 2. Use drugs that affect body weight 3. Type 1 DM 4. Weight loss >5 kg in the past 3 months 5. Diseases that are under diet or exercise control 6. Heart failure&#44; dialysis&#44; cancer

Design outcomes

Primary

MeasureTime frame
Body composition Pre intervention and post intervention dual&#45;energy X&#45;ray absorptiometry,Aerobic fitness Pre intervention and post intervention Peak exercise test,Hematology Pre intervention and post intervention Fasting for 10 hours before testing,Muscle function Pre intervention and post intervention Isokinometer

Secondary

MeasureTime frame
Body composition Pre intervention and post intervention dual&#45;energy X&#45;ray absorptiometry,Hematology Pre intervention and post intervention Fasting for 10 hours before testing,Muscle function Pre intervention and post intervention Isokinometer,Physical performance Pre intervention and post intervention Sit to stand test,Physical performance Pre intervention and post intervention Stair climbing test

Countries

Taiwan

Contacts

Public ContactChiao&#45;nan Chen

National Yang&#45;Ming University

chiaonanchen@gmail.com+886228267000

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026