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Effectiveness of nasal intermittent positive pressure ventilation versus nasal continuous positive airway pressure in preterm infants after less invasive surfactant administration

Effectiveness of nasal intermittent positive pressure ventilation versus nasal continuous positive airway pressure in preterm infants after less invasive surfactant administration

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20180905004
Enrollment
Unknown
Registered
2018-09-05
Start date
2017-01-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Forty one received nIPPV as an initial RS. If nIPPV failed&#44

Interventions

Forty one received nIPPV as an initial RS. If nIPPV failed&#44
surfactant administration was given with the LISA approach and patients continued on nIPPV.
Experimental Device

Sponsors

Sohag University, Egypt
Lead Sponsor

Eligibility

Sex/Gender
All
Age
28 Weeks to 37 Weeks

Inclusion criteria

Inclusion criteria: infants admitted in neonatal intensive care unit, Sohag University Hospital, Egypt with a gestational age of 28–34 weeks, mean ± SD birth weight (1259.44±377.22 grams), suffering from RDS but not requiring intubation in the delivery room were included in the study

Exclusion criteria

Exclusion criteria: Infants with major congenital anomalies, no parental written informed consent, and who required early intubation according to the American Academy of Pediatrics guidelines for neonatal resuscitation, (14) more than 34 weeks or less than 28 weeks, were excluded from the study.

Design outcomes

Primary

MeasureTime frame
need for invasive ventilation within the first seven days of life and the surfactant requiremen day vital sign

Secondary

MeasureTime frame
N/A - -

Countries

Egypt

Contacts

Public ContactRamadan A Mahmoud

Sohag University

ramadan.aboelhassan@yahoo.com00201121806410

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026