Acute kidney injury Acute kidney injury Cirrhosis Novel biomarker
Conditions
Interventions
Hospitalized cirrhotic patients with risk of acute kidney injury but no acute kidney injury detected at the end of day 7 of admission.,Hospitalized cirrhotic patients with risk of acute kidney injury
Diagnostic,Diagnostic
No acute kidney injury,With acute kidney injury
Sponsors
Rachadapisek Sompot Fund
Liver Unit,
Department of Medicine,
Division of Gastroenterology,
Faculty of Medicine,
Chulalongkorn
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Hospitalized cirrhotic patients with risk of acute kidney injury
Exclusion criteria
Exclusion criteria: 1. Chronic kidney disease or need renal replacement therapy 3. Post renal acute kidney injury or acute glomerulonephritis or acute interstitial nephritis 4. Liver or kidney transplant 5. Need for immunosuppressive drug other than for treatment of severe alcoholic hepatitis 6. Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Diagnosis of acute kidney injury by urine LFABP and NGAL compared with serum creatinine Up to 7 days of admission Level of urine LFABP and urine NGAL on the day of acute kidney injury diagnosed by serum creatinine | — |
Secondary
| Measure | Time frame |
|---|---|
| Diagnosis of hepatorenal syndrome and acute tubular necrosis by urine LFABP and NGAL Up to 7 days of admission Level of urine LFABP and urine NGAL on the day of hepatorenal syndrome and acute tubular necrosis di | — |
Countries
Thailand
Contacts
Public ContactSalisa Wejnaruemarn
Unaffiliated
Outcome results
None listed