Correlation between relative afferent pupillary defect (RAPD) and visual field defect on Humphrey automated perimetry

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20180903006

Enrollment

Registered

2018-09-03

Start date

2018-09-04

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The patients are diagnosed with unilateral or asymmetrical bilateral optic neuropathy or retinopathy with having RAPD Relative afferent pupillary defect (RAPD) Visual field defect

Interventions

The patients&#44

diagnosed with unilateral or asymmetrical bilateral optic neuropathy or retinopathy with having RAPD&#44

were assigned to done a CTVF 30&#45

2 test and the patients will be analysed in catagories

Screening

Abnormal RAPD

Eligibility

Sex/Gender

All

Age

20 Years to No maximum

Inclusion criteria

Inclusion criteria: 1) The patients are diagnosed with unilateral or asymmetrical bilateral optic neuropathy or retinopathy 2) The patients have RAPD using neutral density filters and swinging light test 3) The patients are willing and able to provide informed consent to participate in the study 4) The patients are at age above 20 years old

Exclusion criteria

Exclusion criteria: 1) The patients have advance retinopathy or optic neuropathy 2) The patients have pupil irregularity in the abnormal RAPD eye such as posterior synechiae, iris atrophy, post laser peripheral iridotomy or iridoplasty, iris sphincter tear, iridodialysis, neovascular iris, corectopia, and traumatic mydriasis. 3) The patients use one of medications affecting the pupil size: dilating or constricting eye drops 4) The patients have media opacities that obscure pupillary examination or have an effect on visual field analysis such as cataract, corneal opacity, and vitreous hemorrhage 5) The patients are diagnosed with cranial nerve III palsy with pupillary involvement or Horners syndrome 6) The patients cannot perform visual field test with Humphrey automated perimetry program 30-2, SITA-standard strategy 7) The patients with unreliable Humphrey visual filed studies which define as one of these following: I. False-negative errors greater than 30% II. False-positive errors greater than 30% III. Fixation loss greater than 20%

Design outcomes

Primary

Measure	Time frame
the correlations between RAPD and VF parameters After enrollment RAPD by neutral density filters, VF by Humphrey automated perimetry CTVF30-2	—

Secondary

Measure	Time frame
the correlations between RAPD and VF parameters After enrollment RAPD by swinging light test, VF by Humphrey automated perimetry CTVF30-2	—

Countries

Thailand

Contacts

Public ContactJuthamat Witthayaweerasak

Faculty of Medicine, Prince of Songkla University

leklikachang@gmail.com66815992099

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026