Predicting success of nasal high flow therapy in emergency patients with acute hypoxemic respiratory failure by ROX index

Status

Active, not recruiting

Phases

Phase 3

Study type

Observational

Source

TCTR

Registry ID

TCTR20180829006

Enrollment

100

Registered

2018-08-29

Start date

2018-08-29

Completion date

Unknown

Last updated

2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute hypoxemic respiratory failure in emergency patients acute hypoxemic respiratory failure nasal high flow therapy high flow nasal cannula emergency patients

Interventions

nasal high flow

Treatment

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: respiratory rate more than 24 breaths/min use of accessory muscle use or abdominal paradox room air SpO2 equal or less than 90% and need of oxygen supplement via face mask more than 9L/min to maintain SpO2 above 92%

Exclusion criteria

Exclusion criteria: cardiac arrest, arrhythmia, ST-elevation myocardial infarction, respiratory arrest, need for immediate intubation, Glasglow Coma Scale (GCS) 50 mmHg), suspected hypercapnic respiratory failure (chronic obstructive pulmonary disease, obstructive sleep apnea), RR >35 breaths/min or SpO2 9 L/min, pneumothorax and palliative patients

Design outcomes

Primary

Measure	Time frame
accuracy of ROX index 48 hours after treatment area under the curve	—

Secondary

Measure	Time frame
factor influence success rate of nasal high flow therapy no factors,emergency length of stay no hours,hospital length of stay no hours,mortality rate no percentage	—

Countries

Thailand

Contacts

Public ContactNattakrn Praphruetkit

Siriraj Hospital

nattakarn.prp@mahidol.ac.th024199216

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026