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SEMA4D And PAD2 As A Diagnostic Tool For Periodontal Disease Activitiy

Determination Of Levels Of Matrix Metalloproteinase 8, Semophorin 4D And Peptidarginine Deiminase 2 İn Serum And Gingival Fluid İn Periodontally Healthy, Gingivitis And Chronic Periodontitis Subjects

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20180809004
Enrollment
Unknown
Registered
2018-08-09
Start date
2017-06-08
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingivitis&#44

Interventions

Patients with chronic periodontitis disease has been treated with non surgical periodontal therapy. Scaling and root planning has been performed to all patients.
Active Comparator Procedure/Surgery

Sponsors

Izmir Katip Çelebi University Scientific Research Projects Coordinatorship
Lead Sponsor
Izmir Katip Çelebi University Scientific Research Projects Coordinatorship
Collaborator

Eligibility

Sex/Gender
All
Age
20 Years to 55 Years

Inclusion criteria

Inclusion criteria: • Systemically healthy • Non-smoker • Have not used anti-inflammatory, antibiotic and systemic corticosteroid drugs in the last 3 months • Not pregnant or lactating • Have not received periodontal treatment within the last 6 months • At least 20 teeth in the mouth

Exclusion criteria

Exclusion criteria: • During pregnancy and lactation • Have any systemic disease • Smoking • Have had periodontal treatment in the last 6 months • Individuals who have used anti-inflammatory, antibiotic and systemic corticosteroid drugs in the last 3 months

Design outcomes

Primary

MeasureTime frame
difference at 6 months after end of the intervention ELISA

Secondary

MeasureTime frame
depression at 6 months after end of the intervention ELİSA

Countries

Turkey

Contacts

Public ContactMehmet SaÄŸlam

İzmir Katip Çelebi University

dtmehmetsaglam@gmail.com+90 (232) 325 23 71

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026