subjects have caries ≤ two teeth,
Conditions
Interventions
receive 1 lozenge without the probiotic L. rhamnosus SD11,
once daily for 4 weeks under observation by a teacher.,receive 1 lozenge with the probiotic L. rhamnosus SD11,
once daily for 4 weeks under observation by a teacher.
Randomized,
placebo,Blinded,
probiotic
Sponsors
National Innovation Agency
National Innovation Agency
Eligibility
Sex/Gender
All
Age
12 Years to 14 Years
Inclusion criteria
Inclusion criteria: subjects aged 12-14 years old, have caries ≤ two teeth, have an absence of periodontal disease, be a non-smoker, and have daily tooth brushing habits using a fluoride containing toothpaste.
Exclusion criteria
Exclusion criteria: having habitual consumption of probiotics or xylitol, having systemic antibiotic medication taken within 6 weeks, having an allergy to cows’ milk, lactose intolerance, and any severe food allergy, (d) having systemic or severe chronic diseases, and undergoing orthodontic treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cariogenic bacteria 4, 8 weeks Cariogenic bacteria level by real time PCR | — |
Secondary
| Measure | Time frame |
|---|---|
| side effect; diarrhoea, vomiting, fever 8 weels interview | — |
Countries
Thailand
Contacts
Public ContactRawee Teanpaisan
Faculty of Dentistry, Prince of Songkla university
Outcome results
None listed