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Progestin-only and Combined Estrogen-Progestin Contraceptive Pills after Surgery of Ovarian Endometrioma: A Randomized Controlled Study

Progestin-only and Combined Estrogen-Progestin Contraceptive Pills after Surgery of Ovarian Endometrioma: A Randomized Controlled Study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20180725001
Enrollment
Unknown
Registered
2018-07-25
Start date
2018-07-25
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometriotic cyst Endometriosis&#44

Interventions

Progestin&#45
only pill composed of Desogestrel (0.075 mg) prescribe 1 tab per day,Combined pill composed of Ethinyl estradiol (0.02 mg/tab)& Desogestrel (0.15 mg/tab) prescribe 1 tab per day
Active Comparator Drug,Active Comparator Drug
Progestin only pills,Combined oral estrogen&#45
progestin pill

Sponsors

Faculty of Medicine, Ramathibodi Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1) healthy women age 20-45 years 2) diagnose endometrioma size at least 3 cm in diameter and performed laparoscopic surgery already 3) No history of oral hormone within 3 months and no treatment history of รับ depot-medroxyprogesterone acetate (DMPA) or GnRH agonist 9 months before surgery 4) no contraindication for Ethinyl estradiol และDesogestrel 5) no desire for a child within 2 years

Exclusion criteria

Exclusion criteria: 1) liver cirrhosis, chronic renal disease, coagulopathy or has a disease not suitable for surgery 2) have a contraindication to Ethinyl estradiol or Desgestrel 3) cannot tolerate to abnormal uterine bleeding, side effect of progestin-only pills 4) deny participating to the study

Design outcomes

Primary

MeasureTime frame
Pain symptom 0, 3, 6, 12, 18 months visual analogue scale, verbal rating scale

Secondary

MeasureTime frame
Side effect 0, 3, 6, 12, 18 months Bleeding amount and pattern

Countries

Thailand

Contacts

Public ContactAreepan Sophonsritsuk

Ramathibodi Hospital

areepan.sop@mahidol.ac.th0809096531

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026