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Efficacy of internal limiting membrane peeling 1 DD versus 2 DD for treatment of large full thickness macular hole: Randomized Clinical Controlled Trial.

Efficacy of internal limiting membrane peeling 1 DD versus 2 DD for treatment of large full thickness macular hole: Randomized Clinical Controlled Trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20180719001
Enrollment
Unknown
Registered
2018-07-19
Start date
2018-07-20
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Rate of macular hole closure Visual acuity gain in ETDRS letters Complications of surgery Macular hole Internal limiting membrane peeling FTMH

Interventions

Radius of ILM peeling 1DD from foveal center from large FTMH,Radius of ILM peeling 2DD from foveal center from large FTMH
Active Comparator Procedure/Surgery,Experimental Procedure/Surgery
1 DD internal limiting membrane peeling,2 DD internal limiting membrane peeling

Sponsors

None listed

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: full thickness macular hole Age 60 or above Hole size >500 mcm by spectral domain optical coherence tomography(SD-OCT) Able to maintain prone position for 7 days at least

Exclusion criteria

Exclusion criteria: high myopic macular hole traumatic macular hole epimacular membrane vitreomacular traction previous retinal surgery ocular media opacity concurrent ocular disease advanced glaucoma

Design outcomes

Primary

MeasureTime frame
Macular hole closure rate After 3 months, 6 months follow up Measure by spectral domain optical coherence (SD-OCT)

Secondary

MeasureTime frame
Visual acuity After 3 months, 6 months follow up ETDRS letters by ETDRS chart

Contacts

Public ContactSuthasinee Sinawat

Department of ophthalmology, Faculty of Medicine, Khon Kaen university

ssuthasinee@kku.ac.th6643363383

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026