Pharmacogenetics of angiotensin converting enzyme and relationships with angiotensin converting enzyme activity in Thai population

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

TCTR

Registry ID

TCTR20180718001

Enrollment

100

Registered

2018-07-18

Start date

2018-07-23

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ACE inhibitor&#45

Interventions

Healthy volunteers (aged between 19&#45

45 years) will be recruited in the study. All the study participants are Thai. People with hypertension&#44

drinking alcohol will be excluded. Becasue of these affects angiotensin converting enzyme activity.

Basic Science

Thai healthy volunteers

Eligibility

Sex/Gender

All

Age

19 Years to 45 Years

Inclusion criteria

Inclusion criteria: Thai healthy volunteers

Exclusion criteria

Exclusion criteria: 1. Drinking alcohol smoking drug abuse 2. Pregnancy lactation hormonal contraceptive use 3. Steroid and herbal medicines esp Centella asiatica use within 2 weeks before blood collection 4. Underlying diseases hypertension cardiovascular disease thyroid disease diabetes mellitus pulmonary disease cirrhosis leprosy AIDS cancer

Design outcomes

Primary

Measure	Time frame
Angiotensin converting enzyme polymorphisms end of experiment Real-time PCR based alleic discrimination,Angiotensin converting enzyme polymorphisms end of experiment Real-time PCR based alleic discrimination	—

Secondary

Measure	Time frame
Angiotensin converting enzyme activity end of experiment Spectrophotometer assays	—

Countries

Thailand

Contacts

Public ContactAmmara Chaikan

Faculty of Medicine, Thammasat University

ammarachaikan@hotmail.com662-926-9710-1

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026