Healthy Male volunteers,
Conditions
Interventions
Inhalation of olive oil via hot steam for 15 minutes,Inhalation of Zingiber montanum oil via hot steam for 15 minutes
Sham Comparator Dietary Supplement,Active Comparator Dietary Supplement
Inhalation of olive oil,Inhalation of Zingiber montanum oil
Sponsors
Department of Thai Traditional and Alternative Medicine
Eligibility
Sex/Gender
Male
Age
18 Years to 25 Years
Inclusion criteria
Inclusion criteria: 1. Healthy Male volunteers, age 18-25 years old 2. graduated from high school (grade 12) 3. Willing to participate in the study
Exclusion criteria
Exclusion criteria: 1. Brain diseases, previous head injury 2. Nasal obstruction, active rhinorrhea/ rhinitis, sinusitis 3. Anosmia or hyposmia 4. use CNS suppressants such assedatives-hypnotics, anti-depressants, antipsychotics, opioid analgesics, first-generation antihistamines, or alcohol consumption 2 weeks prior enrollment 5. use CNS stimulants such as pseudoephredrine, amphetamines and its derivatives, nicotine, caffeine, methylxanthines 6. Previous brain surgery 7. Hypersensitivity to olive oil or Zingiber montanum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive function pre-inhalation and post-inhalation Montreal Cognitive Assessment (MoCA) ,Mood scales pre-inhalation and post-inhalation VAS for mood/ anxiety/ stress/ alertness,Attention and working memory pre-inhalation and post-inhalation Digit Span forward / backward (Wechsler memory scale),Memory via Verbal fluency test, Word list learning test pre-inhalation and post-inhalation Controlled oral word association test (Halstead-Reitan Neuropsychological battery), word recall test | — |
Secondary
| Measure | Time frame |
|---|---|
| Psychodynamic formulation pre-inhalation and post-inhalation Rorchach (Inkblot) Test | — |
Countries
Thailand
Contacts
Public ContactAssistant Prof. Dr. Warangkana Arpornchayanon
Department of Pharmacology, Faculty of Medicine, Chiang Mai University
Outcome results
None listed