Total Knee Arthroplasty Popliteal plexus block Adductor canal block Local infiltration analgesia Enhanced recovery Opioid free analgesia Total knee arthroplasty
Conditions
Interventions
guided single-
shot sham iPACK block were performed by injecting of 0.9% NSS 5 ml. The cocktail of local infiltration analgesia was done in intra-
operative surgery. Continuous adductor canal block under ultrasound guidance was performed by injecting 0.25% levobupivacaine 15 ml and follow by 0.15% levobupivacaine 5 ml/hr,Ultrasound-
guided single shot popliteal plexus block was performed by injecting of 0.25% levobupivacaine 20 ml and adrenaline (1:200,
000),
The cocktail of local infiltration analgesia was done in intra-
operative surgery. Continuous adductor canal block under ultrasound guidance was performed by injecting 0.25% levobupivacaine 15 ml and follow by 0.15% levobupivacaine 5 ml/hr
Sham Comparator Procedure/Surgery,Experimental Procedure/Surgery
Continuos adductor canal block,
local infiltration analgesia,iPACK block,
Local infiltration analgesia,
Sponsors
none
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patient who was scheduled for total knee arthroplasty at King Chulalongkorn Memorial Hospital ASA class 1 to 3 ASA class 1 A normal healthy patient ASA class 2 A patient with mild systemic disease Mild diseases only without substantive functional limitations ASA class 3 A patient with severe systemic disease but not threaten to life Body mass index BMI between 18 to 40 kg m2
Exclusion criteria
Exclusion criteria: refuse to participate this study unable to cooperate or cognitive impairment eg dementia allergy to any drug in this study contraindication to neuraxial anesthesia eg coagulopathy contraindication to NSAIDs Ketorolac and Celebrex in this study chronic opioids use or diagnosed of neuropathic pain unable to performed Time up and go test
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Post operative opioid consumption 24 hours Milligram of Morphine Consumption | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative Pain Score 0, 4, 8, 12, 24, 36 and 48 hours, 2 and 5 days, 2 weeks, 6 weeks and 2 months Visual Analog Scale,Post operative opioid consumption 12, 48 hours Milligram of Morphine Consumption,Quadriceps Strength Postoperative 0, 1, 2, 3 Days and 3 Months Maximum voluntary isometric contraction,Cumulated Ambulation Score Postoperative 0, 1, 2, 3 Days Rehabilitation after surgery,Postoperative Complication Postoperative 0, 1, 2, 3 Days Postoperative Nausea Vomiting, Fall, Dizziness, Sleep disturbance, Timed up and go test Postoperative 3 Months Rehabilitation after surgery,Delta Timed up and go test Preoperative and 3 months after surgery Rehabilitation after surgery,Length of stays Postoperative to discharge out of hospital Days,Walking aid Postoperative 2 and 5 days, 2 weeks, 6 weeks and 2 months Rehabilitation after surgery | — |
Contacts
Public ContactWirinaree Kampitak
King Chulalongkorn Memorial Hospital
Outcome results
None listed