Diabetes is a major social burden. In 2017,
Conditions
Interventions
Oat fiber,Fibersol
Experimental Dietary Supplement,Placebo Comparator No treatment
Sponsors
Unicity Science
Eligibility
Sex/Gender
All
Age
0 Years to 0 Years
Inclusion criteria
Inclusion criteria: -BMI 23-35 kg/m2 -waist circumference > 80 cm in female or > 90 cm in male -Impaired fasting glucose screening by * fasting blood glucose levels between 6.1 and 7.0 mmol/L (110 and 125 mg/dL) * 2-hour Glucose Tolerance Test with 75 g of oral glucose dose, blood plasma glucose between 7.8 mmol/L (140 mg/dL) and 11.1 mmol/L (200 mg/dL) -No anti-diabetic and lipid-lowering therapy -Stable body weight for at least 6 mo
Exclusion criteria
Exclusion criteria: -Pregnant or lactating females -Persons with known allergies to any ingredients in either the active or placebo study compounds will be also excluded. -People who habitually used a dietary fiber supplement will be also excluded. -Following, or recently followed, a diet plan or supplement or medication use known to affect the trial - Anyone who has had a history of diagnosed type 2 diabetes mellitus, gastrointestinal disease, poorly controlled hypertension (systolic blood pressure > 160 mmHg, diastolic blood pressure > 100 mmHg), renal disease, liver disease, and thyroid disease, as well as severe health condition (e.g., cancer, cardiovascular disease). - participating in any vigorous exercise program
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fasting blood glucose 12 weeks after end of the intervention the automated (enzymatic) method | — |
Secondary
| Measure | Time frame |
|---|---|
| fasting insulin 12 weeks after end of the intervention Chemiluminescence immunoassay (CLIA),blood lipid profiles 12 weeks after end of the intervention Enzymatic colorimetric method,% body fat (body composition) 12 weeks after end of the intervention DXA (Dual X-ray absorptometry) | — |
Countries
Thailand
Contacts
Public ContactWantanee Kriengsinyos
Institute of Nutrition
Outcome results
None listed