Hepatocellular carcinoma is the major cancer problem in Thailand. The treatment for the advanced disease is still very limited. Targeted therapy is very expensive and cannot distributed to all pat hepatocellular carcinoma herbal recipe three roots
Conditions
Interventions
First arm: Experimental group. The patients will take the drug produced by the project. Drug made from herbal recipe. The method used for producing drug following traditional medical usage by grinding
dissolving in distilled water.
,Second arm: Placebo. Patients will take the placebo in the package similar to the real herbs.
Active Comparator Drug,Placebo Comparator Drug
Drug intervention group,Placebo group
Sponsors
Thai Traditional Medical Knowledge Fund
Eligibility
Sex/Gender
All
Age
20 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Male or female with age over 20 years. 2. Diagnosed as hepatocellular carcinoma with no definitive therapy using imaging or tissue biopsy 3. If woman, not in a pregnancy state and can have birth control until the trial finish for at least 3 months 4. no definitive therapy 5. willing to sign in the inform consent
Exclusion criteria
Exclusion criteria: 1. Those with performance status 3,4 2. Complete blood count: absolute neutrophil 5 folds of upper reference range Bilirubin > 3 folds of upper reference range Prolong PT, PTT 3. Those who have breast feeding, not willing to examine of pregnancy test
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| prolong survival 2.5 year statistics method using Kaplan Meier Survival Curve | — |
Secondary
| Measure | Time frame |
|---|---|
| quality of life 2.5year form | — |
Countries
Thailand
Contacts
Public ContactKritiya Butthongkomvong
Udonthani Cancer Hospital
Outcome results
None listed