Striae alba striae alba,
Conditions
Interventions
Each patient’s striae was divided into left and right side. Subjects have been treated with fractional CO2 laser on both sides for three treatments at four weeks interval. Immediately after the lase
each side of striae was randomly assigned to apply rh-
EGF or aloe vera gel and the subjects are required to apply the medication twice daily until 1 month after last laser treatment session.,Each patient’s striae was divided into left and right side. S
EGF or aloe vera gel and the subjects are required to apply the medication twice daily until 1 month after last laser treatment session.
Experimental Drug,Active Comparator Drug
rh-
EGF,Aloe vera gel
Sponsors
Thammasat University
Eligibility
Sex/Gender
All
Age
20 Years to 60 Years
Inclusion criteria
Inclusion criteria: subjects aged 20-60, in good health, with striae alba on both sides of abdomen, thigh or buttock, able to remain 5kg of their starting weight during the study and avoid any non-study treatment of striae during the whole study period
Exclusion criteria
Exclusion criteria: history of keloids or hypertrophic scar, skin infection or other active skin disease on the study areas, use of immunosuppressive drug or systemic retinoid within past 2 months, any treatment including laser for striae within 1 year prior to study initiation, allergy to local anesthesia (e.g. lidocaine or prilocaine).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Texture of striae, Average malanin and melanin variation 9 months Anthera 3D Image | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effectes such as erythema, scab and postinflammatory hyperpigmentation 9 months Investigator assessment | — |
Contacts
Public ContactArisa Kaewkes
Thammasat University
Outcome results
None listed