thyroid carcinoma treated with radioactive iodine radioactive iodine glucose tolerance thyroid carcinoma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Differentiated thyroid carcinoma patients, age 18-75 years who undergo high dose (>100 mcu) RAI. 2. The person who can follow the protocol
Exclusion criteria
Exclusion criteria: 1. abnormal glucose tolerance test 2. impaired plasma glucose, Diabetes mellitus 3. glucocorticoid used 4. creatinine > 1.5 mg/dl 5. liver disease; ALT > 2.5x Upper normal limit 6. previous treatment with radioactive iodine 7. pregnancy/planned pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| insulinogenic index 6 months 75 gm OGTT,insulinogenic index 6 months 75 gm OGTT | — |
Secondary
| Measure | Time frame |
|---|---|
| lipid profile 6 months 75 gm OGTT,Insulin sensitivity index 6 months 75 gm OGTT,Disposition index 6 months 75 gm OGTT, HOMA-IR 6 months 75 gm OGTT,body weight and body mass index 6 months 75 gm OGTT | — |
Countries
Thailand
Contacts
Division of Endocrinology, Faculty of Medicine, Chulalongkorn University