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Effect of slow loaded breathing training on inspiratory muscle strength, exercise capacity and blood pressure in chronic obstructive pulmonary disease with co-existing hypertension

Effect of slow loaded breathing training on inspiratory muscle strength, exercise capacity and blood pressure in COPD with co-existing hypertension

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20180601002
Enrollment
32
Registered
2018-06-01
Start date
2018-06-15
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic obstructive pulmonary disease Slow loaded breathing training Slow breathing training Hypertension High blood pressure SLB&#44

Interventions

Training with respiratory rate of 6 breaths/min (inspiratory time: expiratory time = 3:7) 15 sets/session (rest between set for 5 seconds)&#44
2 sessions/day&#44
every day for 8 weeks. Inspiratory loaded is 20&#45
30% of maximum inspiratory pressure with pursed lip breathing,spontaneous deep breath with pursed lip breathing 6 breaths/min (inspiratory time: expiratory time = 3:7) 15 sets/session&#44
8 weeks.
Experimental Device,Active Comparator Device

Sponsors

None listed

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. COPD patients stage moderate to severe with hypertension 2. Aged between 40-80 years 3. Good communication and cooperation 4. Good cognition with MMSE– Thai 2002 (Mini – Mental State Examination: Thai version) score more than 17 points with full scores are 30 points. 5. Stable COPD without acute exacerbation in the previous 4 weeks 6. Independent physical activity

Exclusion criteria

Exclusion criteria: 1. Medical history related with contraindication of exercise including significant resting ECG suggesting ischemia, recent myocardial infarction, or cardiac event, unstable angina, uncontrolled dysrhythmias with symptoms or hemodynamic compromise and symptomatic heart failure, symptomatic severe aortic stenosis, acute myocarditis or pericarditis, and suspected or known dissecting aneurysm 2. Using oxygen therapy 3. History of renal disease or renal dysfunction, neuromuscular disease: cerebrovascular accident, spinal cord injuries 4. Medical history of pneumothorax, recent lung surgery (within 12 months), and spontaneous rib fractures 5. Pulmonary hypertension or pulmonary edema which unrelated with COPD, pulmonary infection, pneumonitis, pulmonary fibrosis with symptoms, active lung tuberculosis, and interstitial lung disease with symptom 6. Musculoskeletal disorders including; severe osteoporosis, limit shoulder flexion ≤ 90o, Hip or knee Osteoarthritis with pain on movement, Back pain with pain on movement, hand function impairment 7. Secondary hypertension 8. Visual impairment, hearing impairment, Balance impairment 9. Pulse oxygen saturation less than 90% at resting 10. Current smoking 11. Current another exercise training program which effect to results of this study

Design outcomes

Primary

MeasureTime frame
Inspiratory muscle strength Pre-training, Post-training, and sustain period Mouth pressure meter

Secondary

MeasureTime frame
Lung function Pre-training, Post-training, and sustain period Spirometry,Exercise endurance Pre-training, Post-training, and sustain period Spot marching and 6-minute walk distant,Dynamic hyperinflation Pre-training, Post-training, and sustain period Biopac 100 and Arm ergometry,Blood pressure and heart rate Pre-training, Post-training, and sustain period Digital blood pressure and heart rate monitoring ,Quality of life Pre-training, Post-training, and sustain period St George’s respiratory questionnaire ,Dypnea Pre-training, Post-training, and sustain period Modified Medical research council dyspnea scale and COPD Assessment Test ,Exhaled breath temperature Pre-training, Post-training, and sustain period Breath thermometer

Countries

Thailand

Contacts

Public ContactChattarin Wongsawat

Faculty of Associated Medical Science, Khon Kaen University

chattarin_w@kkumail.com+66823162897

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026