FindTrial
Sign In

Establish the factors of predicting cognitive impairment and the effect of exercise intervention on cognitive function in patients with Parkinson’s disease

Establish the factors of predicting cognitive impairment and the effect of exercise intervention on cognitive function in patients with Parkinson’s disease

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20180530004
Enrollment
60
Registered
2018-05-30
Start date
2018-08-01
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild cognitive impairment in Parkinson&#39

Interventions

Patients will underwent a total of 36 sessions&#44
3 sessions per week over a 12&#45
week period. Each session consist of 60 minutes of main exercise including 20 minutes aerobic exercise&#44
20 minutes muscle strengthening and 20 minutes balance training.,Patients will underwent a total of 36 sessions&#44
week period. Each session consist of 60 minutes of main exercise including 20 minutes gait training&#44
20 minutes cognitive training and 20 minutes dual&#45
task training.,Patients will underwent a total of 36 sessions&#44
week period. Each session consist of 60 minutes of main exercise including 20 minutes trunk exercise&#44
20 minutes upper extremity stretching and 20 minutes lower extremity stretching.
Experimental Other,Experimental Other,Active Comparator Other
Multicomponent exercise group,Dual&#45
task training goup,Control exercise group

Sponsors

Mackay Medical College
Lead Sponsor
National Yang&#45
Collaborator
Ming University
Collaborator

Eligibility

Sex/Gender
All
Age
20 Years to 85 Years

Inclusion criteria

Inclusion criteria: Clinical diagnosis of idiopathic PD by a neurologist, Hoehn and Yahr stage I to III, independent walking,at least graduated from elementary school, medical stable, and no cognitive impairment (mini-mental state examination [MMSE] score ≥ 24).

Exclusion criteria

Exclusion criteria: Unstable medical conditions, dementia, drug addicts, tumor history within five years and other comorbid medical diseases known to interfere with participation in this study.

Design outcomes

Primary

MeasureTime frame
Neuropsychological test pre-training, post-training, 3 months follow-up Paper-and-pencil test,quantitative EEG pre-training, post-training, 3 months follow-up Electroencephalograph, EEG,Gait performance pre-training, post-training, 3 months follow-up Single task walking and dual task walking—

Secondary

MeasureTime frame
Disease severity and clinical characteristics pre-training, post-training, 3 months follow-up Unified Parkinson's disease Rating Scale, UPDRS,Quality of life pre-training, post-training, 3 months follow-up Parkinson’s Disease Questionnaire, PDQ-8—

Countries

Taiwan

Contacts

Public ContactFang-Yu Cheng

Mackay Medical College

fycheng@mmc.edu.tw886226360303

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Apr 4, 2026