palmar warts or verruca vulgaris
Conditions
Interventions
applied 3 times per day by using cotton-
tip applicators (CTA) and occluded by bandage (3M Thailand Co.,
Lat Lum Kaew,
Pathum Thani) for at least 1 hour,applied 3 times per day by using cotton-
Pathum Thani) for at least 1 hour
Experimental Drug,Placebo Comparator Drug
topical 15% zinc oxide,Hydrophilic cream
Sponsors
Ratchadaphiseksomphot Endowment Fund
Ratchadaphiseksomphot Endowment Fund
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients older than 18 years with at least 2 similar palmar warts or verruca vulgaris on either one or both hands were eligible. The wart diameter had to range between 2 to 8 millimeters, the total number of lesions had to be at least 2 but not more than 15 and they must have never been treated with any zinc preparations.
Exclusion criteria
Exclusion criteria: Subjects who had recalcitrant warts which were defined as warts unresponsive to any treatment at least 5 times in the past 6 months, those who had known allergy to any formulation of zinc, or categorized as immunocompromised host, e.g. poorly-controlled diabetes mellitus, acquired immunodeficiency syndrome (AIDS), chronic kidney disease, or were treated with immunosuppressive agents by topical or systemic treatment, as well as pregnant or lactating women were excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| size of the lesion (surface area) week 0, 2 and 4 photograph by dermoscopy and analyzed by illustrator CS6 | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effect of topical 15% zinc oxide week 0, 2 and 4 case record form,diameter of the lesion week 0, 2 and 4 photograph by dermoscopy and analyzed by illustrator CS6,volume of the lesion week 0, 2 and 4 Antera camera 3D,patients and physician assessment week 4 score from questionnaire | — |
Countries
Thailand
Contacts
Public ContactPravit Asawanonda
Chulalongkorn University
Outcome results
None listed