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EFFECT OF ADJUNCTIVE PLASMA APPLICATION ON NON-SURGICAL PERIODONTAL TREATMENT OF CHRONIC PERIODONTITIS PATIENTS

EFFECT OF ADJUNCTIVE ATMOSPHERİC PRESSURE COLD PLASMA APPLICATION ON CLINICAL, BIOCHEMICAL AND MICROBIOLOGIC PARAMETERS IN NON-SURGICAL PERIODONTAL TREATMENT OF CHRONIC PERIODONTITIS PATIENTS : A RANDOMIZED CLINICAL TRIAL.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20180522001
Enrollment
Unknown
Registered
2018-05-22
Start date
2016-01-06
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontitis Periodontal pocket Clinical attachment loss Periodontal microbiology Cold plasma Periodontitis Periodontal pocket Anti&#45

Interventions

Single&#45
handed application of non&#45
surgical periodontal therapy on patients with periodontitis.,Adjunctive use of atmospheric pressure cold plasma device with non&#45
surgical periodontal therapy on patients with periodontitis.
Sham Comparator Device,Experimental Device
Non&#45
surgical periodontal therapy. ,Non&#45
surgical periodontal therapy with APCP

Sponsors

The Scientific And Technological Research Council
Lead Sponsor
İzmir Katip Çelebi University
Collaborator

Eligibility

Sex/Gender
All
Age
25 Years to 70 Years

Inclusion criteria

Inclusion criteria: Good general health Patients having at least 12 natural teeth with minimum of three in each jaw quadrant. Two sites in each quadrant with a minimum probing depth of 5 mm.

Exclusion criteria

Exclusion criteria: Smoking Two sites in each quadrant with a minimum probing depth of 5 mm. Pregnancy Lactation Those who had recieved systemic antibiotics or surgical or non-surgical periodontal treatment within the past 6 months. Use of long-term administration of anti-inflamatory medications within the past 3 month Extensive dental prosthetic involvement.

Design outcomes

Primary

MeasureTime frame
Clinical attachment gain Baseline, 30 days and 3 months. Measured using a manual periodontal probe (milimeters)—

Secondary

MeasureTime frame
Probing Pocket Deptth Baseline, 30 days and 3 months. Measured using a manual periodontal probe (milimeters),Biochemical markers (IL-1b, IL-10, VEGF) Baseline, 30 days and 3 months. Enzym Linked Immunosorbant Assay,Bleeding on probing. Baseline, 30 days and 3 months. Measured using a manual periodontal probe (positive-negative),Microbiologic analyzis Baseline, 30 days and 3 months. Quantative Real Time Polymerase Chain Reaction Analyzis—

Contacts

Public ContactDiğdem Küçük

Department of Periodontics, Faculty of Dentistry

digdemkucuk86@gmail.com+905067100266

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026