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An experimental single-case design on the effectiveness of oxytocin on reducing addiction severity index in a patient with oropharyngeal squamous cell carcinoma, the mediation role of emotional dis-regulation

An experimental single-case design on the effectiveness of oxytocin on reducing addiction severity index in a patient with oropharyngeal squamous cell carcinoma, the mediation role of emotional dis-regulation

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
TCTR
Registry ID
TCTR20180511003
Enrollment
1
Registered
2018-05-11
Start date
2014-06-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

All the data of this study were collected after agreement with the patient&#44

Interventions

Since oxytocin is a peptide&#44
delivery through intranasal path is considered as a preferred method in clinical studies (7). Oxytocin intranasal spray (Syntocinon(®)
Novartis&#44
Basel&#44
Switzerland) was including oxytocin plus glycerol&#44
sorbitol&#44
benzyl alcohol and distilled water&#44
that was contained in an amber 7 mL glass nasal spray with a metered pump. Placebo sprays had the same combination but did not contain oxytocin. Each pump spray delivered 50 μL of OT (9 IU) or placeb
Experimental Drug
oxytocin intranasal

Sponsors

none
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: single-case design structure

Exclusion criteria

Exclusion criteria: single-case design structure

Design outcomes

Primary

MeasureTime frame
Addiction severity 14 months and 44 evaluations Addiction severity index—

Secondary

MeasureTime frame
emotion regulation 14 months and 44 evaluations Difficulties in Emotion Regulation Scale (DERS)—

Countries

iran

Contacts

Public Contactbijan pirnia

Bijan Center

b.pirnia@usc.ac.ir+9802122081450

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026