Limbal stem cell deficiency Limbal stem cell deficiency Simple limbal epithelial transplantation Cultivated limbal epithelial transplantation
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Bilateral limbal stem cell deficiency History of allogeneic simple limbal epithelial transplantation (allo-Clinical success in limbal transplantation confirmed by slit-lamp examination, impression cytology and in vivo confocal microscopy
Exclusion criteria
Exclusion criteria: Age below 18 years Clinical failure in limbal transplantation Active ocular infection Pregnancy Inability for follow-ups Inability to cooperate with the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Genetic compatibility of the corneal epithelial cells and cells from donor or recipient At least 3 months after allogeneic limbal stem cell transplantation STR analysis | — |
Secondary
| Measure | Time frame |
|---|---|
| Ocular signs At least 3 months after allogeneic limbal stem cell transplantation Slit-lamp examination | — |
Contacts
Department of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol University