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Genetic identification of corneal epithelial cells after allogeneic simple limbal epithelial cell transplantation and cultivated limbal epithelial transplantation

Genetic identification of corneal epithelial cells after allogeneic simple limbal epithelial cell transplantation and cultivated limbal epithelial transplantation

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
TCTR
Registry ID
TCTR20180510003
Enrollment
20
Registered
2018-05-10
Start date
2018-04-06
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Limbal stem cell deficiency Limbal stem cell deficiency Simple limbal epithelial transplantation Cultivated limbal epithelial transplantation

Interventions

Patients after limbal stem cell transplantation
Basic Science

Sponsors

Faculty of Medicine Siriraj Hospital, Mahidol University
Lead Sponsor
Department of Ophthalmology&#44
Collaborator
Faculty of Medicine Siriraj Hospital&#44
Collaborator
Mahidol University
Collaborator

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Bilateral limbal stem cell deficiency History of allogeneic simple limbal epithelial transplantation (allo-Clinical success in limbal transplantation confirmed by slit-lamp examination, impression cytology and in vivo confocal microscopy

Exclusion criteria

Exclusion criteria: Age below 18 years Clinical failure in limbal transplantation Active ocular infection Pregnancy Inability for follow-ups Inability to cooperate with the study

Design outcomes

Primary

MeasureTime frame
Genetic compatibility of the corneal epithelial cells and cells from donor or recipient At least 3 months after allogeneic limbal stem cell transplantation STR analysis

Secondary

MeasureTime frame
Ocular signs At least 3 months after allogeneic limbal stem cell transplantation Slit-lamp examination

Contacts

Public ContactSuksri Chotikavanich

Department of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol University

suksri_c@yahoo.com02-4198037

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026