FindTrial
Sign In

A randomized controlled comparison of difference systolic blood pressure after the reversal of non-depolarized muscle relaxant with atropine 0.9 mg and 1.2 mg plus neostigmine 2.5 mg in hypertensive patients

A randomized controlled comparison of difference systolic blood pressure after the reversal of non-depolarized muscle relaxant with atropine 0.9 mg and 1.2 mg plus neostigmine 2.5 mg in hypertensive patients

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
TCTR
Registry ID
TCTR20180424004
Enrollment
Unknown
Registered
2018-04-24
Start date
2017-10-09
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

different systolic blood pressure Atropine&#44

Interventions

Atropine 1.2 mg ,Atropine 0.9 mg
atropine 30 second before neostigmine 2.5 mg,atropine 30 second before neostigmine 2.5 mg
Experimental Drug,Experimental Drug

Sponsors

Khonkaen Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1. Elective case for surgery undergo to general anesthesia and receive non depolarizing muscle relaxant 2. Hypertensive patient with SBP 18 year old

Exclusion criteria

Exclusion criteria: Exclusion criteria: 1. Underlying hyperthyroid or any arrhythmia 2. Patient who receive Beta blocker 3. Pregnancy patient 4. Patient who Body Mass Index; BMI > 35 kg/m2 (morbid obesity)

Design outcomes

Primary

MeasureTime frame
different systolic blood pressure every 1 minute for 15 minutes then every 5 minutes until complete 90 minutes of observation. systolic blood pressure,different heart rate every 1 minute for 15 minutes then every 5 minutes until complete 90 minutes of observation. heart rate—

Secondary

MeasureTime frame
different heart rate every 1 minute for 15 minutes then every 5 minutes until complete 90 minutes of observation. heart rate, different diastolic blood pressure every 1 minute for 15 minutes then every 5 minutes until complete 90 minutes of observation. diastolic blood pressure , different mean arterial pressure every 1 minute for 15 minutes then every 5 minutes until complete 90 minutes of observation. mean arterial pressure—

Countries

Thailinad

Contacts

Public ContactRatchayakorn Limapichat

Khonkaen Hospital

kae_racha@hotmail.com0815996759

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026