Skip to content

Anticholinergic Discontinuation and Cognitive Functions in Patients with Schizophrenia: A Pharmacist – Physician Collaboration in the Outpatient Department

Anticholinergic Discontinuation and Cognitive Functions in Patients with Schizophrenia: A Pharmacist – Physician Collaboration in the Outpatient Department

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
TCTR
Registry ID
TCTR20180420002
Enrollment
Unknown
Registered
2018-04-20
Start date
2015-02-01
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia

Interventions

linical pharmacist took responsible to provide pharmaceutical care to all patients. These included conducting a treatment plan by suggested treatment strategies which could help to improve cognitive f
Experimental Drug,Active Comparator Drug
pharmacist intervention group,usual care group

Sponsors

Siam University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1) aged between 18-50 years; 2) had been diagnosed of schizophrenia according to the Diagnostic and Statistical Manual of Mental Disorders, 4th (DSM-IV); 3) received stable agent and dosage regimen of antipsychotics for at least 2 months; 4) had mild to moderate symptoms of schizophrenia which was determined by Brief Psychiatric Rating Scale (BPRS) of 32-54; and 5) had duration of illness after diagnosis of schizophrenia less than 10 years.

Exclusion criteria

Exclusion criteria: Patients were excluded if they had mental retardation, delirium, or had communication impairment which affected the ability to perform cognitive function tests.

Design outcomes

Primary

MeasureTime frame
mean change from baseline of executive function within pharmacist intervention group 12 weeks Wisconsin Card Sorting Test (WCST) perseverative errors

Secondary

MeasureTime frame
mean change from baseline to week 12 of cognitive tests between between 12 weeks Wisconsin Card Sorting Test (WCST) perseverative errors ,mean change from baseline to week 12 of psycho between pharmacist intervention and usual care groups 6 and 12 weeks Brief Psychiatric rating scale,proportion of patients who had a clinical response of psychopathological symptoms 6 and 12 weeks Brief Psychiatric rating scale

Contacts

Public ContactThanompong Sathienluckana

Siam University

thanompong.sat@gmail.com+668 3276 1419

Outcome results

None listed

Source: TCTR (via WHO ICTRP) · Data processed: Aug 9, 2026