Hemifacial spasm on botolinum toxin Hemifacial spasm Botolinum toxin Facial massage facail exercise
Conditions
Interventions
Patients within intervention groups are introduced facial squeezing technique by video-
program before the injection of BTX-
A (The technique is shown in appendix 5 according to the protocol,
modified from the original one of O’Reilly et al.16) After BTX-
A injection the patients are then asked to squeeze his/her faces immediately after the injection for 5 minutes as assigned. ,While the patients who are allocated to no facial exercise group are asked
Experimental Procedure/Surgery,No Intervention No treatment
BTX-
A injection plus facial exercise using squeezing technique for 5 minutes ,No facial exercise (BTX-
A injection alone)
Sponsors
Faculty of Medicine, Siriraj Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: - Patients with diagnosis of hemifacial spasm by authorized neurologist in Siriraj Hospital, Mahidol University, Bangkok, Thailand - Patients are currently treated with BTX-A in the clinic with any degree of response - Age 18-80 years
Exclusion criteria
Exclusion criteria: - Patients who have other neurological problems e.g. stroke, blepharospasm, dementia - Patients who are physically dependent - Patients who are illiterate - Patients who are blind - Patients who cannot squeeze his/her own face - Patients currently treated with oral anticoagulants (NOACs, Vitamin K antagonists)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The efficacy of treatment measured by QoL with HFS-30 severity score 3 months HFS 30 score,Time to onset of drug 3 months Days | — |
Secondary
| Measure | Time frame |
|---|---|
| SMC grading system, time to peak effect, duration of BTX-A effect 3 months days | — |
Countries
Thailand
Contacts
Public ContactPrachaya Srivanitchapoom
SIriraj hospital
Outcome results
None listed